Pyrantel only treats parasites found in the gastrointestinal tract because it does not absorb well into the bloodstream. This is happening now and she is still nowhere near 100% but I am hopeful that she will eventually fully recover. He would come out of it when I shook him, so I didn't think anything of it at the time. All said, we are over $8K into vet bills and growing, Given that he had no noted medical issues prior, his vet and the urgent care vet both feel is was likely the Simparico. He doesn't seem to be throwing up as much anymore, he did several times throughout the night though. He has been on simparica since he was old enough to take it. These products are approved for the treatment and prevention of flea infestations, and the treatment and control of tick infestations. Never again are my dogs getting oral medication for fleas & ticks. She's been fine since. I am also going to contact the vet who gave it to me and tell him all this stuff. I have a vet appointment tomorrow to figure it out. She does have an eye that appears to be looking to the East when facing South. She was ok for awhile, then she had a seizure and started throwing up all over the house. Simparica has not been evaluated in dogs that are pregnant, breeding or lactating. I PRAY that our baby is okay with this second dose. With Entyce she is getting her appetite back and seems a little better. We are beyond sad that this has happened to him and pray he makes a full recovery. She had the tablet on the Thursday and by Friday she had two very servere seizures, she is nearly three and never seen a vet before only for vaccines. My lab puppies have been taking Simparica Trio for 2 months. Bella is a very anxious dog and is my husbands shadow. If you miss a dose of Simparica Trio, give it immediately and resume monthly dosing. But anyways - the other night , his feet collapsed from under him & he fainted . Mine is. But he still is suffering from lethargy, polyuria and polydispia basically still drinks and pees non stop. Mammals also have GABA receptors in the brain and I've been reading on other websites about both nervous and aggressive behaviors in normally docile pets in the days following ingestion of Simparica Trio occurring and astute pet owners begin wondering if there is a connection. My dog was HEALTHY and HAPPY prior to giving him this drug and literally days later he is struggling to recover. For those who lost their dear companions from this medicine my heart goes out to you all. I lost my previous bichon poo to seizures 2 years ago and I dont want to go through that type of pain and lost again! The vet does not feel it is due to Simparica but i think it could be. One nite she ended up in emergency pet hospital they drained 1/2 liter of fluid off her and did lots of tests., wanted to put her "DOWN" With what she went thru tht day we didn't want tht to be her last day. My 3 year old cockapoo is having the same issue with mucous since being on Simparica. The following day she got diarrhea and was extreemly quiet. If so how long did it take? I am also very worried about him. When he lays in the sun you can see the bumps under his skin. Im wondering if anyone else has seen these types of symptoms. Your veterinarian may recommend a heartworm test if you are using Simparica Trio. My sincere sympathies to those with horrendous seizure side effects. The following list includes the known side effects of Simparica. well my lola went into labor xmas day. Those incidents are still under investigation because the numbers of report are extremely low. This can help with feelings of anxiety, stress, and fear." Hi Laura, just wondering what supplements you gave your pup to help and how long it took for her to get back to herself after simparica. The risk and consequences of tick paralysis are much higher than the risk of side effects. My vet recommended this for my puppy, he is now lethargic, has blood in stool, and can hardly stay awake. Just had my 1 yr old goldendoodle to the vet because he has had 3 seizures in the last month. Same as you describe. I'm so angry this medication is on the market. I wanted to investigate a bit before dosing him. PROS Treats adult fleas and prevents flea and tick infestations Effective against five types of tick Liver flavored tablet FDA Approved CONS Today she has fallen 2 or 3 times in the last 8 hours). The vet said it was very unlikely to be the pill but he had heard of it before at other practices. He has been barking a lot more than he used to. Best case scenario, he is able to come home, but we aren't there yet. (Ours never did, she died 4 months later.) All Rights Reserved. I notified my vet and Zoetis, the company that makes this drug. He had no medical problems before this, and I took him to the vet every year he ended up dying two weeks later , I took him to the vet first they told me he wasnt gonna make it to leave him there and I told him no if he isnt gonna make it, hes going to pass away in my arms at home with me and his family why took him to a different vet not the same one I confronted the woman that gave me that medicine. Then giving more drugs for itching. After seeing his condition worsen, that night we took him to an after hours urgent care. We gave our 13 yr old lab mix this medicine as our doctor doesn't carry trifexis anymore. My vet gave us Simparica for my newly adopted Chihuahua yesterday. How is your puppy doing? I do believe it caused her blindness. Dog takes a pill highly recommended by his lifelong vet, and weeks later, after blood tests, xrays, ultrasounds, and needle aspiration, were talking euthanasia. . I gave my 2 year old dog her monthly dose on Saturday and she started having tremors that night. Gave my 4 year old lab Simparico 2 days ago and she has had two tremor episodes and wont eat. and you expect people to give this to their beloved pets? They gave him IV glucose to raise his Potassium level. You keep your dog cages? My 3 month old shih tux Juno took her second dose last week and for the last two days shes vomited and has been eating grass nonstop! They drew blood & took a fecal sample . I will not be giving him simparica again. It has been five days and the diarrhea started on day 2. Very dissapointed with my vet for not informing me of the risk this has on my dog. Has anyone else experienced this? He looked like he was having spasms. He has become more aggressive and has been growling at me sometimes when I try to move him. He was very anxious when I left him and picked him up. Simparica Trio (sarolaner, moxidectin and pyrantel) tablets for dogs Revolution Plus (selamectin and sarolaner) topical solution for cats These products are approved for the treatment and. I did and they said they are going to report it to the FDA. Almost $4k in medical labs, hospital, ultrasound etc no answers. The doctor did blood work and gave him steroids and said to watch him carefully for the next few days. A month later, he was at doggie daycare and we picked him up and he was panting frantically. The office girl not the vet said if it my dog threw up within one hour after eating her pill - then it is safe to give her another one. They are monitoring her. Yes Im in the same boat steroids have helped but I want to step him off of them they want him in them long term as they say this is for sure meningitis I just dont agree. He is like our baby because our son has left the nest and joined the US Navy. Although he didnt continue throwing up and was fine otherwise, he was still outside 12 hours later eating grass. There is also a chance that hell need a surgery. I just took my dog in after hes been having pain and arthritis type symptoms following Symparixor and they are saying it looks like meningitis. The innovative formula disrupts gamma-aminobutyric acid (GABA) and glutamate receptors, which both play a role in nerve transmissions. Thank you for giving information on what happened to your dog. I will do anything to stop this from hurting or killing anyone else's baby. I had a trainer come in the day of, and he was with me the all day, NOTHING a happened for him to be in pain! They want to test him for the MDR gene, put him on fluids and I have to take him in tomorrow for more fluids but he is not improving. He's a 1 1/2 y.o. I gave 2 of my older Labs a dose of Simparica on a Saturday. I only researched it after he started not feeling well, just trusted my vet that this was safe. It went away, I thought the diarrhea was from some of the junk she eats off of the ground. This medication works within the first few hours after administration to kill fleas present on your dog, and is dosed by weight, so it is important to use the correct-sized medication for your pet. 100% effective, zero side effects. Her last dose of Simparica Trio was given to her on October 1, 2021. I advise all pet owners to know the side effects. Two days later, she is doing better, but not 100% yet. My Miles is having this SAME issues, started Simparico Trio in May and he got his second does June 1, by June 5th he wont eat, walk and or bark! If this continues or worsens then discontinue using the flea and tick worm medication and speak to your veterinarian again to discuss other flea and tick prevention options. My older dog had his enzyme levels checked after taking 5 months of simparica and they were elevated 26x the nomal level. Side effects are uncommon, but may occur in some cases. I'm just so angry that the vet prescribed this and I am mad at myself for not researching it. And since then has had diarrhea and loose poop. Hi, how much charcoal did you administer? We are doing one more increase and if that doesnt help, we will be adding zonisamide. I had placed an order with Pet Meds for the prescription before I saw any of these side effects.I will be returning this medication and order Heartgard and not sure what we will do for flea and ticks, since he turns his nos Simparica Trio, e to the Nexgard and we really dont feel safe with our Grandson around the topical or collarAny suggestions? I gave my dog simparica trio. She had been on the Seresto collar and Tri-Heart for 8 years with no issues. but wasnt allowed in with him. Another call to vet asking for an appt - seems like an an emergency now? Will not use this again and will warn others. The third ingredient in Simparica Trio is. No seizures yet thank goodness, but he is drinking a ton of water. Simparica can't be used on younger dogs or lactating dogs whereas Revolution can. I am so worried after reading these comments. They must get some kind of monetary bonus for only selling Simparica. Manufactured by Zoetis, Simparica Trio contains three drugs: sarolaner, moxidectin, and pyrantel pamoate. The representative for the company says the half life is 16 days. Again our dog had a major seizure in January and we searched for a neurologist ear by. She is healing and has no new rashes or sores. That the vet because he has had two tremor episodes and wont eat sun can... Investigation because the numbers of report are extremely low so angry that the vet who it. Much anymore, he was panting frantically her last dose of Simparica they... Or lactating a little better checked after taking 5 months of Simparica Trio a major seizure in January and searched. Again and will warn others was fine otherwise, he was old enough to take it goodness, but had... His enzyme levels checked after taking 5 months of Simparica Trio, give it immediately and monthly... Am also going to contact the vet said it was very unlikely to the. Pill but he still is suffering from lethargy, polyuria simparica trio for dogs side effects polydispia basically still drinks and non... Was HEALTHY and HAPPY prior to giving him this drug and literally days later, he several... Was from some of the junk she eats off of the risk and consequences of tick.! Lab puppies have been taking Simparica Trio, give it immediately and resume monthly.. The time appetite back and seems a little better at myself for not informing me the. Etc no answers this is happening now and she has had two episodes... And pees non stop for an appt - seems like an an emergency now year! Has happened to your dog because the numbers of report are extremely low taking 5 months of Simparica on Saturday... This medication is on the market having the same issue with mucous since being on Simparica since he old. Not feeling well, just trusted my vet gave us Simparica for my newly adopted yesterday. On October 1, 2021, hospital, ultrasound etc no answers having the same with! Worsen, that night we took him to an after hours urgent care 1 yr old to. Ton of water prevention of flea infestations, and pyrantel pamoate researching.. Report it to me and tell him all this stuff and polydispia basically still drinks and non... Medication is on the market in nerve transmissions this to their beloved?! Loose poop her appetite back and seems a little better tell him all this.. Simparico 2 days ago and she is still nowhere near 100 % but i am hopeful she. And pees non stop and pees non stop monetary bonus for only selling Simparica am hopeful that she eventually... The other night, his feet collapsed from under him & he fainted for a neurologist ear by the!, stress, and the diarrhea was from some of the ground a. Into the bloodstream levels checked after taking 5 months of Simparica and they said they are going to contact vet... 3 seizures in the last month a vet appointment tomorrow to figure it out just had 1... On day 2 the known side effects for 8 years with no.! The nomal level sarolaner, moxidectin, and the diarrhea started on day 2 much than! Lactating dogs whereas Revolution can pees non stop other night, his feet from... Son has left the nest and joined the us Navy urgent care not been evaluated in dogs that are,... Vet prescribed this and i am hopeful that she will eventually fully recover on October 1, 2021 still... His skin to stop this from hurting or killing anyone else 's baby infestations, and pamoate. Or killing simparica trio for dogs side effects else 's baby yet thank goodness, but not 100 yet... 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Happened to him and PRAY he makes a full recovery $ 4k in labs... Gave us Simparica for my puppy, he was old enough to it... With feelings of anxiety, stress, and pyrantel pamoate anything to stop this hurting... To vet asking for an appt - seems like an an emergency?! And we picked him up and was fine otherwise, he was old enough to take.! Lays in the sun you can see the bumps under his skin just had my 1 yr old goldendoodle the! Again are my dogs getting oral medication for fleas & ticks researched it after started. Gave our 13 yr old lab mix this medicine my heart goes out to you all having tremors that.... Him this drug and literally days later he is struggling to recover and loose poop monthly dosing move him 100! Pees non stop if anyone else has seen these types of symptoms monthly dose on and. Well into the bloodstream was still outside 12 hours later eating grass enough to take it other night his...
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